Oxymetholone is without a doubt the strongest and most visibly active steroid to date. Not only does it act very rapidly, it causes a virtual explosion of mass. Gains of up to 10 pounds in 2 weeks are not uncommon. This is largely due to a moderate to low androgenic effect combined with a high anabolic activity also mediated by non-AR mechanisms (mechanisms other than simply binding the androgen receptor). You can imagine that the gains made on oxymetholone aren't the leanest. You would note a drastic smoothing out of the muscle due to estrogen-related fat (lipolysis) and water retention. This lipolysis has been shown to be rather drastic. One study1 on long-term hemodialysis patients showed beyond a doubt the role that oxymetholone can play in causing hyperlipedemia. The fat deposition rate, post-hepatic (after processing by the liver), increased drastically in the oxymetholone group while numbers remained stable in the control group.
The most common daily dose of Anapolon is 100mg, but even at that dosage side-effects like water-retention, elevated blood pressure, acne, hair loss, blood clotting changes, gynocomastia, liver toxicity and mood swings are very often reported. Using aromatase inhibitors to control estrogen aromatization will be ineffective as this drug does not directly convert into estrogen. It was suggested that oxymetholone can activate the estrogen receptor, similar to, but more profoundly than the estrogenic androgen methandriol. Supplements like Milk Thistle can be taken to help keep liver enzyme levels between safe ranges.
Realize that there are two orals in this dieting regimen. This is just an example. You can pick any number of combos. Just be sure to give it thought by way of drug mechanism of action, and interaction (synergy) as we’ve said before. The above example is a great cutting regimen for general purposes. Two orals ran together at a sane dosage for ten weeks once or twice a year should be fine on your liver, as long as you are respecting your liver the rest of the year. I am not talking about those who go out drinking three nights a week while trying to get lean. If you are going to do this at all, reserve your liver for filtering drugs that have a purpose. Remember that this is hypothetical and for information purposes only.